Welcome to the Villeneuve Lab

The Villeneuve Lab is interested in how the brain ages, with a specific focus on factors that modify the association between brain lesions and cognitive performance. Our research is motivated by the fact that more than 25% of older adults are considered cognitively normal despite the presence of beta-amyloid in their brain, a hallmark of Alzheimer’s disease. This fact suggests that other factors interact with beta-amyloid to trigger cognitive deficits in Alzheimer’s disease. It also suggests that actions can be taken to prevent or postpone disease-related symptoms. The main focus of the Villeneuve Lab’s research is therefore to examine the factors that protect against, or worsen, the development of cognitive deficits in age-related neurodegenerative diseases.

We use a multi-tier approach that includes molecular PET imaging, MRI imaging, neuropsychological testing and genetics, combined with analytic tools such as deep learning, lasso regression and partial least squares regression.

Visit our research page to learn more about our ongoing projects.

We currently have one funded Postdoctoral position available.


Recent News

Pierre-François Meyer defends his PhD thesis
4 November 2019

Pierre-François Meyer successfully defended his PhD thesis, entitled “Immune mechanisms as predictors of cognitive impairment and therapeutic targets in pre-symptomatic Alzheimer’s disease.” Congratulations!

group photo

6 October 2019

The Canadian television series Découverte featured Dr. Villeneuve and the work of the PREVENT-AD research group in an episode about Alzheimer’s disease. This episode aired on October 6, 2019 on ICI Radio-Canada Télé and can be watched online here.

Sylvia appears on episode of Découverte


Farewell to Our First Graduating Master’s Student
1 September 2019

The Villeneuve Lab team bids farewell to Melissa McSweeney, our first graduating Master’s student. Melissa joined our lab in August 2017 and has been a Master’s student for the last 2 years. Melissa has contributed significantly to the lab and has helped manage the lab. We wish her all the best with her new career.



Healthy Brains for Healthy Lives (HBHL) Fellowships
15 August 2019

Congrats to Alexa, Hazal and Pierre on receiving Healthy Brains for Healthy Lives (HBHL) Fellowships for the upcoming year.

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