Philosophy

Our lab has three guiding principles in research:

• Being dynamic and passionate about the questions we are targeting.
• Being creative and open minded about novel ideas and new research techniques.
• Always aiming for rigorous and high-impact work conducted in a collaborative setting.

Current research projects

• To target early amyloid and tau deposition and propagation.
• To test the interplay between AD pathology and vascular pathology.
• To assess which lifestyle factors protects against AD pathology and clinical expression.
• To determine the genetic factors that influence AD pathology and clinical expression.

Biomarkers studied in the lab

• Cognition (subjective and objective decline)
• Biochemical markers
  • CSF markers (i.e. amyloid, tau, ApoE levels, inflammatory markers)
  • Blood markers (i.e. ApoE, fractionated cholesterol)
• Multimodal neuroimaging
  • PET (amyloid, tau, FDG)
  • MRI (Volume, thickness, RS, DTI, FLAIR, ASL)